News

As someone trying to get insurance to pay for one of these drugs, you've pretty much listed the reason. I spent so long trying to find a pattern but have given up, going back to my childhood I've never felt satiated. I never feel full, so I have to rely on other cues. I can eat a huge meal, of any variety, and I'll still feel hungry after (and during). The only modes my appetite has are "hungry" and "if you don't eat you'll die". I've had various meds "help" in one way or the other but none lasted, and none have changed the sensation of hunger. The thought of not feeling hungry makes me want to cry, it sounds so surreal.

Exactly. To make a comparison, it's like telling a person with depression to just stop feeling sad.

That's why you can't fix the problem without exercise.

You can justify eating more when you're burning more calories.

When I burn 4000 or 5000 calories in a day, I can eat an unlimited amount of food, and often don't make up the deficit. So, it becomes all-you-can-eat with weight loss.

Also, it's important to note that "being hungry all the time" is a symptom of poor eating habits and undernutrition. A lesson in how to eat is going to help someone more than pills.

I think the credibility of the argument that "it's not easy to just lose weight" goes down when the contenders for solutions are "more pills" vs. "Lifestyle change".

Its always better to try the non-pill option before deciding the pills are needed. American policies and support structures need massive overall. Even things that seem totally unrelated like more mixed use and walkable city Zoning policies will make Americans more active and less dependent on meds.

It is the least complicated thing on earth. If you burn more calories than you consume, you will lose weight. It is a scientific law and while I'm no doctor, I'm certain that 99.9% of the population is beholden to it.

It is not more complicated than that. If you eat less you will lose weight. I was almost 350 lbs after years of eating too much. I decided it was enough and started intermittent fasting. Lost 90 pounds in the first year or two. I did not change my diet, just lowered my calories.

After about a year I hit a wall at 60 pounds lost and wasn't going down anymore. So I just shortened my eating window and started losing again. I've been fasting for about 6 years now and it's completely changed how I handle food. I am able to tell my body when it is and isn't time to eat. I rarely feel hunger anymore.

My 60+ year old father and mother both saw the results I had and started fasting as well. My father has lost more weight than me.

It is as simple as not eating.

How dramatically does the base metabolic rate change? Surely you can reduce caloric intake more than base metabolic rate would go down. I restrict my calories with great results, sometimes I'll do a 24 hour fast if I've eaten too much junk and I feel great afterward. I've kept my weight in check for years while restricting caloric intake. This is all diet, since I don't do exercise (I need to get better at that). I can see myself gaining all that weight back if I get into the mindset of "well, I lost that weight, I'm free to enjoy food without restriction again!" It's kind of like sobriety, it takes continual diligence to keep your progress.