this post was submitted on 07 Jun 2025
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[–] Flamekebab@piefed.social 36 points 1 day ago (12 children)

It's bizarre to me that someone can make it to adulthood without knowing that paracetamol specifically is no fucking joke.

[–] raltoid@lemmy.world 24 points 1 day ago* (last edited 1 day ago) (1 children)

People look up resources on them and see that the recommended max dose of ibuprofen is lower than paracetamol per day in weight of the active ingredient and stop reading.

They don't get to the part about how the effect per weight isn't the same. Or how damaging paracetamol can be for the liver if you take it regularly or go over the recommend limit. Heavy drinkers especially don't take into account the extra stress on their liver, which is a contributor to the 400-500 deaths it causes every year in the US alone.

Meanwhile ibuprofen makes you feel sick and want to vomit once you start to go over the recommended limit. And if you reach that stage, you basically just stay hydrated to keep your kidneys going and wait for it to pass. Since it usually takes another 2-3 times as much to for the severe effects to occur.


To quote Scrubs:

Dr. Cox: Did you just page me to ask me how much ibuprofen to give Mrs. Lenzner here?

Sunny: Well, I was worried it would exacerbate the patient's

Dr. Cox: It's ibuprofen! Here's what you do. When she wakes up, get her to open her mouth nice and wide, then get some of those ibuprofen pills in your hands and throw them at her. Whatever sticks in there, that's the correct dosage.

And in the pilot episode, it was J.D. and regular strength Tylenol.

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[–] Mustakrakish@lemmy.world 1 points 17 hours ago (7 children)

I try and avoid painkillers whenever possible for two reasons:

  1. They're crazy addictive
  2. They build tolerance, and when it comes time where taking them is unavoidable, I want them to work as well as possible.
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[–] sxan@midwest.social 28 points 1 day ago (5 children)

You know what else is stupid? Pain management in the US. I get that you need to be careful about addiction, but the idea that people should have to suffer pain because we're having a pain medication "reefer madness" spasm is idiocy.

The guy just kept taking them until his teeth stopped hurting. Why is the alternative that he just has to put up with being in pain?

[–] sulgoth@lemmy.world 27 points 1 day ago (1 children)

The fact that the drug companies lied about the addictiveness of their product so doctors were handing them out like candy didn't help.

[–] Dozzi92@lemmy.world 11 points 1 day ago

Yeah, it was rampant here in Jersey, and we're definitely still feeling the effects. Things that didn't need opiates got opiates. And guess what? Lotta people all of a sudden need them for life. And it wasn't just Oh, here's your script. Doctors were knowingly abusing it for profit. So like with most things in life, some people ruin it for everyone else.

[–] RBWells@lemmy.world 9 points 1 day ago (2 children)

Yes it is. I have had, over my 40 years as migraineuse (they started in my teens) 5 intractable migraines. Meaning less than once every 5 years I get one that lasts days, I cannot eat or drink, just puke. I used to be able to go to my doctor and get shot up with opiates and Phenergan, so much of it, they would do one dose, come back later, another, another, another, until finally I would say "it still hurts but I don't care" and go home nodding like a junkie, sleep and wake up with no headache, and, importantly, NO desire for more drugs.

Now the opiates are not allowed because they didn't work. But nothing works on the status migraine. Now they give you a cold cocktail IV of some sort of Advil and nausea medicine and it doesn't work either, and costs $2,000 because it can only be done in the emergency room not the doctor office.

It's adding insult to injury. There has to be some way to make these available for acute situations at least.

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[–] joel_feila@lemmy.world 8 points 1 day ago

We have never had good pain management here. Claiming babies can't feel pain, black people hace higher pain tolerance, etc etc. then we swung into really permissive use with oxycodone for a while.

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[–] Ledivin@lemmy.world 86 points 1 day ago (32 children)

American here: I know paracetamol is acetaminophen, but how much is a packet?

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[–] joel_feila@lemmy.world 11 points 1 day ago (6 children)
[–] oo1@lemmings.world 2 points 21 hours ago (1 children)

I think in UK paracetamol is sold over the counter in 28 x 500mg tablets most commonly. Larger packs or higher strengths are prescription only I think.

So 1 pack should last 3.5 days at the max adult dose of 8 per 24h - but I think it'd recommend seeing your doctor if you get into a second pack and you're still using that maximum dosage.

Generally shops will limit sales to 2 packs, but it's easy to shop around so that's no limit.

[–] wewbull@feddit.uk 1 points 19 hours ago (1 children)

I don't know where you'd get packets of 28x500mg.

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[–] Damage@feddit.it 44 points 1 day ago (6 children)

PSA: stupidity is dangerous

[–] Bytemeister@lemmy.world 32 points 1 day ago (4 children)

Yeah, how long until this idiot cooks this liver too?

Honestly, getting a liver transplant in a week is the most unbelievable part of this story.

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[–] shadowedcross@sh.itjust.works 18 points 1 day ago (2 children)

It's people like this who make other people think any amount of painkillers is bad, and seem to get a sense of superiority about them for never taking any.

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[–] Alaik@lemmy.zip 8 points 1 day ago (2 children)

ITT: People who don't know the difference between acute and chronic ODs and how a smaller amount over a long period can hurt you. 325mg APAP x4 will not kill you short term.

The problem was taking it every day over a long period.

Its still fucking stupid though.

[–] prole@lemmy.blahaj.zone 2 points 19 hours ago* (last edited 16 hours ago) (1 children)

I think the problem here is the word "packet" and what that means here exactly. Would be much more clear if they listed the amount of mg, or at the very least, how many pills are in a "packet"

I'm like 99% sure they took way more than just 4 Tylenol.

[–] Alaik@lemmy.zip 1 points 17 hours ago* (last edited 17 hours ago) (1 children)

I've only ever seen "packets" contain two pills or capsules. 325x2x4= 2,600mg or 2.6g, well below the 8g average one time adult OD dose.

Taking less than 3g a day for <3 days is fine, although if you're needing that much you probably should see a medical professional about something more tailored to your type of pain.

Really though way too many people in general have the idea pain killers of any type should remove all pain and in many cases, that's not realistic without long term health complications.

Edit: lemmy did not like me using asterisks for multiplication.

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[–] the_crotch@sh.itjust.works 2 points 21 hours ago

325mg APAP x4 will not kill you short term.

Yeah I'm p sure the daily maximum on the package is 4k

[–] NocturnalMorning@lemmy.world 53 points 1 day ago* (last edited 1 day ago) (10 children)

That guys a moron. The bottles are very very clear not to take more than the recommended dosage. Its labeled all over the bottle.

[–] leisesprecher@feddit.org 44 points 1 day ago

I'm kind of pissed that such obvious and preventable idiocy leads to an almost immediate liver transplant.

Yes, that's just a lucky coincidence for him, but still...

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[–] OmegaLemmy@discuss.online 4 points 1 day ago

I had intense tummy aches for 15 days where I couldn't walk and needed to keep heat to my belly to even function, once my pain killers didn't work, I didn't push it, I just tried to handle the pain

I cried a lot in that time, it fucking sucked, but it sure was better than liver failure.

[–] FundMECFSResearch@lemmy.blahaj.zone 32 points 1 day ago (9 children)

I mean this is just dumb. Like I’m sorry but this would happen with basically every medicine or drug. They aren’t made to be taken at higher doses than advised.

(Imagine you took 8 liters of beer per day for 3 days, you’d be half dead too.)

Moderation people…

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[–] then_three_more@lemmy.world 14 points 1 day ago (6 children)

It's why in the UK shops won't sell more than 2 packets at a time. It's statistically reduced the amount of people killing themselves with them (intentionally or by mistake).

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