this post was submitted on 07 Jun 2025
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Microblog Memes

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[–] leadore@lemmy.world 10 points 1 day ago* (last edited 1 day ago) (1 children)

How much is a "packet"? edit: never mind, I found several conflicting answers in the other comments, no need to add even more and add to the confusion.

[–] Revan343@lemmy.ca 4 points 1 day ago
[–] Atelopus-zeteki@fedia.io 20 points 1 day ago

He's not the first one to 'kill his liver' with paracetamol/ acetominophen (tylenol). First case I recall, the person was taking tylenol nightly with a glass of wine. Here's some links on the current understanding of Liver injury and paracetamol:

Apparently it's not always overdosing: Paracetamol-induced hepatotoxicity at recommended dosage (https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2796.2003.01097.x)

Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update (https://pmc.ncbi.nlm.nih.gov/articles/PMC4913076/) "...in the United States, in particular, it accounts for more than 50% of overdose-related acute liver failure and approximately 20% of the liver transplant cases."

Risk Factors for Hepatotoxicity Due to Paracetamol Overdose in Adults (https://www.mdpi.com/1648-9144/57/8/752) "In the univariable analysis, significant hepatotoxicity risk factors were male gender, alcohol abuse, an ingested paracetamol dose, and a timespan from ingestion to hospital admission. The later one was the only significant risk factor in the multivariable model (adjusted odds ratio 1.08; 95% CI: 1.03–1.12)."

Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease (https://pubmed.ncbi.nlm.nih.gov/37436926/) "Where data were available, we estimate that paracetamol is involved in 6% of poisonings, 56% of severe acute liver injury and acute liver failure, and 7% of drug-induced liver injury."

Understanding paracetamol-induced liver failure (https://link.springer.com/article/10.1007/s00134-014-3293-9)

[–] RestlessNotions@sh.itjust.works 14 points 1 day ago (1 children)

Everyone's discussing ODing on OTC pain meds but the bigger part of this story is why he's in so much pain for so long without being able to see a Dr and receive treatment for chronic pain.

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[–] ObviouslyNotBanana@lemmy.world 13 points 1 day ago (5 children)

I mean... Yeah. There are instructions on the packet. They aren't supposed to be eaten like candy.

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[–] Allonzee@lemmy.world 0 points 20 hours ago* (last edited 20 hours ago)

Just tell them you believe a billionaires earn their money, climate change is a hoax to sell books, and the solution to mass shootings is to sell more guns to more people.

You know, express the nonsensical opinions only a well deluded American is propagandized from birth to express with a straight face when they should be embarrassed at their belligerent ignorance.

[–] muntedcrocodile@lemm.ee 8 points 1 day ago (2 children)

They should have just printed him a Darwin award on a piece of single ply toilet paper and sent him on his way.

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[–] blargle@sh.itjust.works 10 points 1 day ago (4 children)

Isn't this why they specifically put acetaminophen in opioid+nsaid prescription painkillers, instead of ibuprofen or aspirin or naproxen? Just to discourage abuse because if you take too much it'll destroy your liver. Has always seemed a bit fucked up to me.

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