this post was submitted on 08 May 2025
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Moderna's combo Covid and flu mRNA shot outperforms current vaccines in large trial (www.nbcnews.com)
submitted 1 day ago* (last edited 1 day ago) by MicroWave@lemmy.world to c/health@lemmy.world
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A combination shot would make it easier for people to get vaccinated against Covid and the flu at the same time.

Moderna’s combined Covid and flu shot outperformed the existing standalone vaccines for both viruses, according to the results of a phase 3 clinical trial published Wednesday in theJournal of the American Medical Association. 

The vaccine uses the same messenger RNA technology as Moderna’s approved Covid vaccine.(There are no approved mRNA-based flu shots.)

The trial, funded by Moderna, included more than 8,000 adults ages 50 and older who were enrolled in October and November 2023. For people ages 50 to 64, the new vaccine was compared to Moderna’s Covid vaccine and the flu shot Fluarix. For people 65 and older, it was compared to the Covid vaccine and a different flu shot, called Fluzone, which is a stronger dose typically given to older adults. The trial participants either got the existing shots, or the new combination vaccine plus a placebo shot. (This way, both groups got two injections.)

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[–] ddash@lemmy.dbzer0.com 76 points 1 day ago (5 children)

“Immunologically, what’s happening in each cell is they’re acting as if they’ve been infected with both viruses, and so your immune system is going to respond and make the type of inflammation that you would if you had flu or Covid or both simultaneously,” he said.

This will 100% be taken out of context by anti-vaxx crowds.

[–] Randelung@lemmy.world 6 points 13 hours ago

It's nothing new, though. Vaccines have always worked like this - make your body go through the motions without problematic invasive organisms.

[–] jagged_circle@feddit.nl 1 points 16 hours ago

Nah those people think covid is the flu and isnt a big deal

[–] JudahBenHur@lemm.ee 5 points 1 day ago (2 children)

honestly so fucking what? let those jokers not get the vaccination. get sick, have permanent symptoms that last your whole life, fuck it, whatever.

in the meantime, my sleeves are pre-rolled up for this shot, put it in my veins doc, I like not basically dying, its kind of a fetish

[–] prole@lemmy.blahaj.zone 11 points 1 day ago (2 children)

I feel like we've had this discussion a billion times since 2019... Do you really still not understand herd immunity?

[–] JudahBenHur@lemm.ee 8 points 1 day ago

Since 2019 I have given up entirely on collective common sense coming from anybody. People are just far too stupid and selfish to get their shit together if it even inconveniences them a tiny bit. I can only do my best to protect myself as relying on people writ large is a fools errand.

[–] shalafi@lemmy.world -1 points 16 hours ago (1 children)

I'm with the person you replied to. All my empathy is burned the fuck out. All I can do is care for me and mine. If these people are too dumb to get a shot, they're far too dumb to be educated on herd immunity. I've given up.

[–] ExtantHuman@lemm.ee 3 points 50 minutes ago

It's not about empathy for them.

Antivaxxers being walking petri dishes puts the rest of who are vaccinated at risk, because that shit is being given chances to further evolve to bypass our boosted defenses.

[–] ApexHunter@lemmy.ml 2 points 23 hours ago (1 children)

Good luck getting it at all. One of those jokers is head of the HHS and is actively adding obstacles to vaccine approvals.

[–] JudahBenHur@lemm.ee 2 points 21 hours ago

I live in Ireland ¯_(ツ)_/¯

[–] jonne@infosec.pub 12 points 1 day ago (2 children)

Terrible explanation as well.

[–] Ledericas@lemm.ee 3 points 7 hours ago

they should call it bivalent vaccine, since its 2 in 1.

[–] Nurse_Robot@lemmy.world 3 points 1 day ago (1 children)

Is it? I understood it. How would you explain it?

[–] jonne@infosec.pub 16 points 1 day ago (1 children)

They use inflammation instead of antibodies for one.

[–] Nurse_Robot@lemmy.world 3 points 20 hours ago (1 children)

Antibodies create an inflammatory response, seems like we're really nitpicking here. It's a layman's explanation, not a research study or textbook.

[–] 13igTyme@lemmy.world 3 points 7 hours ago

"It does a thing to mimic the bad thing and then the thing gets better so you don't get the real thing."

[–] 0101100101@programming.dev 3 points 1 day ago* (last edited 15 hours ago)

No need to take it out of context. They hear the word "vaccine", smirk at the dumb sheep and shout AUTISM!!!111