Virus is just a program that tries to whatever its malicious intent is while being as minimal and portable as it gets. It it’s a ransomeare to encrypt all your data or a program that looks for passwords in your files, it can still be fairly successful when running through Wine. There is a chance through, that it assumes typical paths where Windows keeps files and if it never tries other drives than C, it will only affect Wine prefix and not your actual files.

You can run Bottles in Flatpak and cut out access to any of your files if you’re afraid it can be malicious